五个普通人在接受器官移植后获得了超能力，并必须与一位超级反派对抗。
民国初期，西北漠城有一座大农场。农场里的工人大多是被农场主人马进荣通过各种手段骗来，从事着繁重的劳动工作，为了防止工人逃跑，马进戎雇佣了大批的 看护。逃跑虽时有发生，却无一成功。刘铁生四人终于在一个雨夜成功逃跑。第二天一早马进荣就得知了刘铁生四人逃跑还杀了自己儿子，盛怒之下，马进荣花费重 金悬赏，并派有“西北狼”之称的侄子马廷风带人追捕。
The King of Queens and Pall Blart: Mall Cop star Kevin James is set to star in the new action comedy Guns Up, playing an ex-cop and family man who moonlights as a mob henchman. When a job goes horribly wrong and both of his worlds collide, he has one night to get his family out of the city.
